Magnesium for Sleep: How Women Over 40 Can Rest Better

You’ve probably tried most things: the weighted blankets, the expensive mattress upgrades, perhaps even a different brand of bedtime tea. I know I have. And still, a decent night’s sleep feels elusive. If you’re a woman over 40 like me, you’re not imagining it. There’s something many overlook that could make the difference, and it just might be in your supplement cupboard already.

For years, magnesium was mainly associated with muscle cramps. But emerging research suggests that magnesium benefits for sleep go far beyond that. It’s one of the most valuable minerals for improving sleep quality, especially for women over 40 navigating the hormonal ups and downs of perimenopause and beyond

Why Women Over 40 Struggle with Sleep: Magnesium's Role

Many women over 40 experience disrupted sleep—not simply because they’re getting older, but because hormonal changes during perimenopause affect vital processes in the body. Magnesium for women over 40 plays a critical role in addressing these changes and improving sleep quality.

As oestrogen levels fluctuate and gradually decline, the way the body uses magnesium changes quite dramatically. And when you factor in the additional stress from balancing work, family, and caring for ageing relatives, cortisol (the stress hormone) can climb higher, further depleting magnesium stores.

The result: the nervous system struggles to switch into proper rest mode.

Magnesium is key for activating the parasympathetic nervous system, which helps your body switch from “fight or flight” to “rest and digest”. It also supports melatonin regulation, essential for natural sleep-wake cycles. Insufficient magnesium can leave your body craving rest while your nervous system stays active.

Magnesium and Sleep: What Science Says

This isn’t just a passing trend—several studies have outlined the links between magnesium benefits for sleep and how it supports better rest for women over 40. Research shows that magnesium can improve sleep quality, regulate melatonin, and reduce stress hormones like cortisol. In one study, women who supplemented with magnesium daily for eight weeks fell asleep faster, slept for longer, and enjoyed better overall sleep quality. Levels of melatonin and cortisol, crucial sleep-related brain chemicals, showed improvement at the same time.

Other research highlights that boosting magnesium intake, whether from food sources or supplements, can promote muscle relaxation and support better sleep. Rather than “forcing” sleep, magnesium helps restore the body’s own natural resting rhythm.

Not All Magnesium Is Equal

It’s well established that different forms of magnesium, such as magnesium glycinate and magnesium citrate, are absorbed and used by the body in distinct ways. Each offers specific benefits, especially for women seeking magnesium for better sleep and relaxation.

Magnesium oxide, while widely available and inexpensive, is not well absorbed and often causes digestive discomfort. For many, it falls short when it comes to supporting relaxation or restful sleep.

In contrast, magnesium glycinate (aka ‘magnesium bisglycinate’), which is magnesium bound to the amino acid glycine, is much better absorbed and gentle on the digestive system. Glycine itself has calming properties, which may make this form particularly useful for those struggling with sleep or looking to quiet a restless mind.

But that’s just the beginning. Other common types of magnesium each have their own story:

• Magnesium L-threonate stands out for its ability to cross the blood-brain barrier. Recent research suggests it can increase brain magnesium levels, with measurable effects on cognitive function, memory, and mental alertness. One double-blind study found that adults taking magnesium L-threonate not only improved their deep and REM sleep, but also experienced better daytime energy and improved mood.

• Magnesium malate combines magnesium with malic acid, a compound involved in energy production in our cells. This form is known for its high bioavailability, and has shown particular promise for supporting muscle health and reducing symptoms of fatigue. Some research links magnesium malate to relief from muscle soreness and even chronic pain conditions, making it a popular choice for those who want to stay active and energised.

• Magnesium citrate is widely recognised for its excellent absorption and its ability to gently draw water into the intestines. This makes it a common choice for those seeking relief from mild constipation, but its benefits go further. Studies indicate magnesium citrate can also help with muscle relaxation, reduce arterial stiffness (a risk factor for heart disease), and support healthy blood pressure and blood sugar levels. There’s growing evidence it may ease symptoms of stress and anxiety and support better sleep thanks to its role in calming the nervous system. However, higher doses may lead to looser stools or mild digestive upset in some people.

• Magnesium chloride is another highly absorbable form, valued for its versatility. It is often used to correct magnesium deficiency and is sometimes chosen for topical applications (such as sprays or bath flakes). Magnesium chloride plays a role in muscle and nerve health, supports steady heart rhythm, helps regulate blood pressure, and assists the body in absorbing calcium for bone health. Evidence also suggests it can aid in blood sugar regulation and maintaining electrolyte balance. Many people find it gentle on the digestive system, though it can cause loosened stools if taken in large doses.

Because of their different yet intertwined actions, for women looking to cover their bases across sleep, cognition, muscle health, and daily energy, supplements that combine several forms of magnesium may offer the most well-rounded support. By harnessing the unique benefits of different types, you can create a daily routine that works in tandem to meet the changing needs of your body—especially through midlife and beyond.

What Science Says About Taking Magnesium

Research continues to reveal further potential advantages of meeting your body’s magnesium needs beyond sleep. Magnesium benefits for women over 40 include improved hormonal balance, better bone health, and enhanced energy levels. These include:

• Blood sugar stability: Adequate magnesium may help support balanced blood sugar levels, which some have found beneficial in reducing early-morning awakenings linked to blood sugar drops.

• Bone health support: As oestrogen levels fall, bone density becomes increasingly important. Magnesium is involved in healthy bone formation and may help slow the progression of osteoporosis.

• Assisting vitamin D utilisation: Magnesium aids the body in using vitamin D efficiently—a nutrient with wide-ranging health benefits.

Magnesium, therefore, delivers a cascade of positive effects throughout the body, serving as more than just a sleep aid.

The Bottom Line

Struggles with sleep after 40 are usually not down to age alone; they can be rooted in an overlooked nutritional deficiency. Magnesium for sleep and relaxation is a simple, science-backed solution for women over 40 looking to improve their rest and overall well-being. Research continues to shine a spotlight on the importance of magnesium not just for sleep, but also for hormonal balance, bone health, blood sugar regulation, and even mood. And as we’ve seen, not all magnesium types are created equal.

• Magnesium glycinate stands out for its gentle support of relaxation and quality sleep.

• Magnesium L-threonate offers unique cognitive and mood benefits, particularly through its action within the brain.

• Magnesium malate may help women with energy, muscle health, and managing chronic aches.

• Magnesium citrate is valued for its high absorption and digestive support, easing muscle tension and promoting restful sleep.

• Magnesium chloride provides a highly bioavailable option for replenishing body stores, supporting nerves, muscles, heart, and overall hydration.

Combining different forms, such as glycinate for relaxation, L-threonate for cognitive support, malate for energy, citrate for digestion, and chloride for overall balance, may offer the most comprehensive support, especially during and after the hormonal shifts of perimenopause. Sometimes, the smartest strategy is a blend that covers all bases instead of relying on just one type.

So, while sleep gadgets and new wellness trends promise quick fixes, evidence shows that nourishing your body with the right blend of magnesium forms can be a practical, science-backed piece of the puzzle. For many women in midlife, restoring this essential mineral can make all the difference—not only at bedtime, but in day-to-day vitality and wellbeing.

References

1. WebMD. Health Benefits of Magnesium Citrate. https://www.webmd.com/diet/health-benefits-magnesium-citrate

2. Health.com. Health Benefits of Magnesium Citrate. https://www.health.com/magnesium-citrate-8607721

3. Healthline. Types of Magnesium and Their Benefits. https://www.healthline.com/nutrition/magnesium-types

4. Verywell Health. What Is Magnesium Chloride? https://www.verywellhealth.com/magnesium-chloride-4768643

5. Olympia Pharmacy. What Is Magnesium Chloride? https://www.olympiapharmacy.com/blog/what-is-magnesium-chloride/

6. PMC. Magnesium-L-threonate improves sleep quality and daytime functioning. https://pmc.ncbi.nlm.nih.gov/articles/PMC11381753/

7. Medical News Today. What to know about magnesium threonate. https://www.medicalnewstoday.com/articles/magnesium-threonate

8. Liv Hospital. Magnesium Malate. https://www.livhospital.com/en/magnesium-malate

9. Health.com. Health Benefits of Magnesium Malate. https://www.health.com/magnesium-malate-8603883

10. Dr. Axe. Magnesium Malate. https://draxe.com/nutrition/magnesium-malate/

11. Dr. Brighten. (2025). Magnesium glycinate for menopause sleep and relaxation. Retrieved from https://drbrighten.com/magnesium-for-menopause/

12. Healthline. (2024). Magnesium for Menopause: Efficacy, Benefits, and Side Effects. Retrieved from https://www.healthline.com/nutrition/magnesium-for-menopause

13. Integrative Women's Health Institute. (2024). Top 5 Supplements for Menopause Sleep Disturbances. Retrieved from https://integrativewomenshealthinstitute.com/menopause-sleep-disturbances/

14. The Better Menopause. (2024). Magnesium supplement effects on sleep quality and duration. Retrieved from https://thebettermenopause.com/en-us/blogs/the-better-gut-community/magnesium-menopause

15. The Menopause Dietitian. (2024). Magnesium and sleep - does it help? Retrieved from https://www.themenopausedietitian.co.uk/magnesium-and-sleep-does-it-help/

16. The 'Pause Life. Magnesium For All Stages Of Menopause. Retrieved from https://thepauselife.com/blogs/the-pause-blog/magnesium-for-all-stages-of-menopause